Creutzfeldt-Jakob disease and bovine spongiform encephalopathy

Bovine spongiform encephalopathy and new variant Creutzfeldt-Jakob disease.

Bovine spongiform encephalopathy (BSE) and Creutzfeldt-Jakob Disease (CJD) belong to a group of degenerative neurological disorders collectively known as the transmissible spongiform encephalopathies (TSEs). The group also includes scrapie of sheep and goats, kuru of humans, chronic wasting disease of mule deer and elk and transmissible encephalopathy of mink. These fatal diseases cause behavio...

Bovine Spongiform Encephalopathy, Creutzfeldt-Jakob Disease and Immunizations

BSE (bovine spongiform encephalopathy) is a progressive neurological disorder of cattle, and has been called “mad cow disease.” Its symptoms are similar to “scrapie,” a brain disease that occurs in sheep. Cattle affected by BSE experience progressive degeneration of the nervous system. Affected animals may display changes in temperament, such as nervousness or aggression, abnormal posture, inco...

Bovine Spongiform Encephalopathy and Its Relationship to Creutzfeldt-jakob Disease

Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) with amyloid angiopathy.

A case is reported of Creutzfeldt-Jakob disease associated with amyloid infiltration of cerebral vessels. The duration of progressive dementia was only 4 months. Neuritic plaques were not a feature of the pathology. This report emphasises the association of spongiform encephalopathy with the presence of amyloid in the brain.

The epidemics of bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease: current status and future prospects.

The large epidemic of bovine spongiform encephalopathy (BSE) in the United Kingdom has been in decline since 1992, but has spread to other countries. The extensive control measures that have been put in place across the European Union and also in Switzerland should have brought the transmission of BSE under control in these countries, provided that the measures were properly enforced. Postmorte...